How can the testing of API calls be done?

Testing of API calls can be done in isolation or in sequence to vary the order in which the functionality is exercised and to make the API produce some useful results from these tests. Designing tests is essentially designing sequences of API calls that have a potential of satisfying the test objectives.This in turn boils down to designing each call with specific parameters and to building a mechanism for handling and evaluating return values.
Designing of test cases depends on the following criteria:
- What value should a parameter take?
- What values together make sense?
- What combination of parameters will make APIs work in a desired manner?
- What combination will cause a failure, a bad return value, or an anomaly in the operating environment?
- Which sequences are the best candidates for selection?

Some of the interesting problems for testers are:
- Ensuring that the test harness varies parameters of the API calls in ways that verify functionality and expose failures. This includes assigning common parameter values as well as exploring boundary conditions.
- Generating interesting parameter value combinations for calls with two or more parameters.
- Determining the content under which an API call is made. This might include setting external environment conditions like files, peripheral devices and also the internal stored data that affect the API.
- Sequencing API calls to vary the order in which the functionality is exercised and to make the API produce useful results from successive calls.